ARMCX3

Across TCGA cell cohorts, ARMCX3 mutation is significantly associated with the drug of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMCX3-associated genes across cancer lineages are LCL161, GSK2801, and SGC-CBP30. Each is linked with ARMCX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMCX3-to-partner and partner-to-ARMCX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCL161 grouped by ARMCX3-low versus ARMCX3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMCX3→partner) and Y-score (partner→ARMCX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCL161 →	+0.439	+2.646	.006	.047	3	1
LARGE_INTESTINE	GSK2801 →	+0.390	+2.678	.013	.037	3	1
LARGE_INTESTINE	SGC-CBP30 →	+0.339	+2.649	.015	.046	2	1
LARGE_INTESTINE	GSK2110183B →	+0.606	+2.649	.047	.046	2	1
LARGE_INTESTINE	OF-1 →	+0.285	+2.646	.049	.047	2	1
LARGE_INTESTINE	CZC24832 →	+0.279	+2.646	.032	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

LCL161 by ARMCX3 expression — LARGE_INTESTINE

Explore this box plot interactively →