ARMCX1

Across TCGA patient cohorts, ARMCX1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMCX1-associated genes across cancer lineages are eIF4E, ACC1, and p62 Lck ligand. Each is linked with ARMCX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMCX1-to-partner and partner-to-ARMCX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by ARMCX1-low versus ARMCX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMCX1→partner) and Y-score (partner→ARMCX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.142	+3.472	.041	.002	3	2
UCEC	ACC1 →	+0.311	+2.472	.009	.010	3	2
UCEC	p62 Lck ligand →	+0.279	+2.916	.009	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.611	+2.434	.001	.001	3	2
UCEC	14-3-3_beta →	-0.143	-2.249	<.001	<.001	3	1
UCEC	Fibronectin →	-0.255	-1.652	.019	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

eIF4E by ARMCX1 expression — UCEC

Explore this box plot interactively →