ARMCX1

Across TCGA cell cohorts, ARMCX1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ARMCX1-associated genes across cancer lineages are ACP4, GPR119, and PSMB11. Each is linked with ARMCX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMCX1-to-partner and partner-to-ARMCX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACP4 grouped by ARMCX1-low versus ARMCX1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMCX1→partner) and Y-score (partner→ARMCX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ACP4 →	+0.016	+3.196	<.001	.007	3	1
SKIN	GPR119 →	+0.019	+3.196	.002	.007	3	1
SKIN	PSMB11 →	+0.012	+3.766	.003	.004	3	1
SKIN	KCNK16 →	+0.030	+3.345	.001	.007	3	1
CNS	DCANP1 →	+0.004	+3.058	<.001	.003	3	1
LARGE_INTESTINE	TBX5 →	+0.218	+3.626	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ACP4 by ARMCX1 expression — SKIN

Explore this box plot interactively →