ARMC9

Across TCGA patient cohorts, ARMC9 mutation is significantly associated with the RNA expression of many other genes, with 3,355 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMC9-associated genes across cancer lineages are RPL35AP3, UBE2L2, and NPAT. Each is linked with ARMC9 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARMC9-to-partner and partner-to-ARMC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL35AP3 grouped by ARMC9-low versus ARMC9-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC9→partner) and Y-score (partner→ARMC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RPL35AP3 →	+0.165	+5.758	<.001	.003	3	3
CESC	UBE2L2 →	+0.098	+3.064	.001	.007	3	2
UCEC	NPAT →	+0.477	+2.330	.001	.003	3	2
UCEC	EI24 →	+0.475	+3.850	<.001	<.001	3	2
UCEC	DLAT →	+0.619	+2.201	<.001	<.001	3	2
UCEC	SRFBP1 →	+0.543	+3.754	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,355 associations by consensus.

RPL35AP3 by ARMC9 expression — LIHC

Explore this box plot interactively →