ARMC6

Across TCGA cell cohorts, ARMC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,620 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARMC6-associated GO terms across cancer lineages are Positive regulation of nuclear cell cycle DNA replication, rRNA metabolic process, and Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with ARMC6 in more than 17 cancer types. Because this analysis shows association rather than direction, both ARMC6-to-partner and partner-to-ARMC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of nuclear cell cycle DNA replication grouped by ARMC6-low versus ARMC6-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC6→partner) and Y-score (partner→ARMC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of nuclear cell cycle DNA replication →	+0.188	+1.011	<.001	.002	3	18
BONE	rRNA metabolic process →	+0.145	+0.970	<.001	<.001	3	18
BONE	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.131	+0.851	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	IMP biosynthetic process →	+0.166	+1.000	<.001	<.001	3	18
BONE	rRNA processing →	+0.134	+0.953	<.001	<.001	3	18
BLOOD_Myeloma	Maturation of SSU-rRNA →	+0.133	+0.978	.002	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,620 associations by consensus.

Positive regulation of nuclear cell cycle DNA replication by ARMC6 expression — PANCREAS

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