ARMC6

Across TCGA cell cohorts, ARMC6 mutation is significantly associated with the RNA expression of many other genes, with 826 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC6-associated genes across cancer lineages are MIOX, SCML2, and TNFSF13B. Each is linked with ARMC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC6-to-partner and partner-to-ARMC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIOX grouped by ARMC6-low versus ARMC6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC6→partner) and Y-score (partner→ARMC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MIOX →	+0.241	+3.212	.008	.006	3	1
LARGE_INTESTINE	SCML2 →	+0.953	+3.212	.009	.006	3	1
LARGE_INTESTINE	TNFSF13B →	+0.511	+3.385	.001	.004	3	1
LARGE_INTESTINE	NISCH →	+0.756	+3.212	.002	.006	3	1
LARGE_INTESTINE	INTS10 →	+0.608	+3.212	.009	.006	3	1
LARGE_INTESTINE	SH3GL2 →	+0.987	+3.252	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 826 associations by consensus.

MIOX by ARMC6 expression — LARGE_INTESTINE

Explore this box plot interactively →