ARMC6

Across TCGA cell cohorts, ARMC6 mutation is significantly associated with the mutation status of many other genes, with 3,691 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC6-associated genes across cancer lineages are NUP210, ROCK2, and SEMA6D. Each is linked with ARMC6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARMC6-to-partner and partner-to-ARMC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUP210 grouped by ARMC6-low versus ARMC6-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC6→partner) and Y-score (partner→ARMC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	NUP210 →	+4.044	+5.000	.008	.008	1	3
CNS	ROCK2 →	+4.044	+5.000	.008	.008	1	3
CNS	SEMA6D →	+4.044	+5.000	.008	.008	1	3
CNS	TGFB1I1 →	+5.044	+5.614	.003	.003	1	3
CNS	EXOG →	+6.044	+6.044	.001	.001	1	3
CNS	ACOX1 →	+5.044	+5.614	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

NUP210 by ARMC6 expression — CNS

Explore this box plot interactively →