ARMC3

Across TCGA pan-cancer cohorts, ARMC3 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ARMC3 data layer compared with 21 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ARMC3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ARMC3 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LSCC and LUAD are the cancer types where ARMC3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.620	0.955	.001	39	view →
LUAD	OS	Quartile	All	0.925	0.423	.006	7	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ARMC3–LSCC (OS)

Open the LSCC breakdown →