ARMC2

Across TCGA cell cohorts, ARMC2 mutation is significantly associated with the RNA expression of many other genes, with 542 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC2-associated genes across cancer lineages are ZNRF4, TMSB4Y, and LCN1. Each is linked with ARMC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC2-to-partner and partner-to-ARMC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNRF4 grouped by ARMC2-low versus ARMC2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC2→partner) and Y-score (partner→ARMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	ZNRF4 →	+0.018	+4.196	<.001	.006	3	1
BREAST	TMSB4Y →	+0.018	+4.232	<.001	.002	3	1
BREAST	LCN1 →	+0.039	+3.672	<.001	.006	3	1
BREAST	SIX6 →	+0.037	+4.247	<.001	.005	3	1
BREAST	DEFB134 →	+0.122	+4.614	<.001	<.001	3	1
BREAST	CSNKA2IP →	+0.005	+3.672	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 542 associations by consensus.

ZNRF4 by ARMC2 expression — BREAST

Explore this box plot interactively →