ARMC2-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ARMC2-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ARMC2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ARMC2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ARMC2-AS1 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KICH, LUSC, and KIRC are the cancer types where ARMC2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARMC2-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHAllAll−0.702<.0019view →
LUSCAllII,III,IV−0.833<.0016view →
KIRCMaleIII,IV+0.368.0186view →
LUADAllII,III,IV−0.760.0015view →
CHOLAllII,III,IV+0.715<.0014view →
THCAFemaleAll−0.598<.0014view →
BRCAAllAll−0.474<.0014view →
KIRPAllIV+0.612.0402view →
STADAllAll+0.295.0402view →
HNSCAllIII,IV+0.267.0352view →
READAllAll+0.826.0471view →
ESCAAllAll−0.533.0351view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ARMC2-AS1–KICH

Tumor-vs-normal expression box plot for ARMC2-AS1 RNA in KICH.

Open the KICH breakdown →

Exploration