ARMC12

Across TCGA patient cohorts, ARMC12 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMC12-associated genes across cancer lineages are Caspase-7-cleavedD198, Shc_pY317, and 14-3-3_beta. Each is linked with ARMC12 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARMC12-to-partner and partner-to-ARMC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ARMC12-low versus ARMC12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC12→partner) and Y-score (partner→ARMC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.633	+1.604	.005	.041	3	3
UCEC	Shc_pY317 →	-0.146	-2.807	.012	.003	3	2
UCEC	14-3-3_beta →	-0.083	-1.664	.030	.023	3	1
UCEC	MEK1 →	+0.331	+1.678	.018	.023	3	1
UCEC	p21 →	+0.173	+2.183	.018	.033	3	1
UCEC	XBP1 →	-0.149	-1.678	.005	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Caspase-7-cleavedD198 by ARMC12 expression — UCEC

Explore this box plot interactively →