ARMC10

Across TCGA patient cohorts, ARMC10 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMC10-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tem, and CD4+ memory T-cells. Each is linked with ARMC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC10-to-partner and partner-to-ARMC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by ARMC10-low versus ARMC10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC10→partner) and Y-score (partner→ARMC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.025	+3.260	<.001	.002	3	1
UCEC	CD8+ Tem →	+0.004	+4.896	<.001	.036	3	1
UCEC	CD4+ memory T-cells →	+0.022	+2.840	.027	.002	3	1
UCEC	aDC →	+0.107	+2.815	.008	.036	2	1
UCEC	CD8+ naive T-cells →	+0.040	+2.823	.007	.036	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD8+ T-cells by ARMC10 expression — UCEC

Explore this box plot interactively →