ARMC10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARMC10 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC10-associated genes across cancer lineages are TMCO5A, GPR171, and FAM162B. Each is linked with ARMC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC10-to-partner and partner-to-ARMC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMCO5A grouped by ARMC10-low versus ARMC10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC10→partner) and Y-score (partner→ARMC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETMCO5A →+0.027+4.415<.001.00731
LARGE_INTESTINEGPR171 →+0.019+4.273<.001.00631
LARGE_INTESTINEFAM162B →+0.158+4.095<.001.00931
LARGE_INTESTINEOR4A47 →+0.022+5.022<.001.00231
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TMCO5A by ARMC10 expression — LARGE_INTESTINE

Box plot of TMCO5A in ARMC10-low vs ARMC10-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration