ARMC10

Across TCGA cell cohorts, ARMC10 mutation is significantly associated with the mutation status of many other genes, with 1,743 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC10-associated genes across cancer lineages are SEC14L3, SPECC1L, and YPEL1. Each is linked with ARMC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC10-to-partner and partner-to-ARMC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEC14L3 grouped by ARMC10-low versus ARMC10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC10→partner) and Y-score (partner→ARMC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SEC14L3 →	+3.350	+4.584	.003	.003	1	1
LARGE_INTESTINE	SPECC1L →	+2.865	+4.217	.007	.007	1	1
LARGE_INTESTINE	YPEL1 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	SNRPD3 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	SH3BP1 →	+4.672	+5.329	<.001	<.001	1	1
LARGE_INTESTINE	HPS4 →	+2.865	+4.217	.007	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,743 associations by consensus.

SEC14L3 by ARMC10 expression — LARGE_INTESTINE

Explore this box plot interactively →