ARMC1

Across TCGA pan-cancer cohorts, ARMC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ARMC1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ARMC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARMC1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

HNSC, PDAC, and GBM are the cancer types where ARMC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.527	0.777	.010	20	view →
PDAC	OS	Quartile	II,III,IV	1.000	0.641	.002	19	view →
GBM	DFS	Tertile	All	0.952	0.688	<.001	13	view →
LUAD	OS	Median	All	0.925	0.757	.003	11	view →
CCRCC	OS	Median	All	0.909	1.000	.019	9	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ARMC1–HNSC (DFS)

Open the HNSC breakdown →