Across TCGA patient cohorts, ARL9 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL9-associated genes across cancer lineages are IGFBP2, JNK2, and NF2. Each is linked with ARL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL9-to-partner and partner-to-ARL9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL9→partner) and Y-score (partner→ARL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-1.072	-3.000	.004	.037	3	1
UCEC	JNK2 →	+0.257	+3.000	.025	.037	3	1
UCEC	NF2 →	+0.271	+3.000	.030	.037	3	1
UCEC	STAT5a →	+0.544	+3.000	.018	.037	2	1
UCEC	PCNA →	+0.264	+3.000	.034	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ARL9 survival (RNA) · tumor vs normal (RNA) · all ARL9 data types