ARL6IP5

Across TCGA pan-cancer cohorts, ARL6IP5 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ARL6IP5 data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ARL6IP5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ARL6IP5 expression acts as an unfavorable survival marker.

COAD, UCEC, and SKCM are the cancer types where ARL6IP5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	II,III,IV	0.056	0.853	<.001	36	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	All	0.210	0.781	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ARL6IP5–COAD (OS)

Open the COAD breakdown →