ARL6IP5

Across TCGA patient cohorts, ARL6IP5 mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL6IP5-associated genes across cancer lineages are ATP2B2-IT1, RNA5SP419, and RNA5SP410. Each is linked with ARL6IP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL6IP5-to-partner and partner-to-ARL6IP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP2B2-IT1 grouped by ARL6IP5-low versus ARL6IP5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6IP5→partner) and Y-score (partner→ARL6IP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP2B2-IT1 →	+0.046	+3.582	<.001	.002	3	2
UCEC	RNA5SP419 →	+0.575	+2.492	.001	.002	3	2
UCEC	RNA5SP410 →	+0.570	+2.204	.001	.006	3	2
UCEC	RNA5SP422 →	+0.715	+2.478	.001	.001	3	2
UCEC	RNA5SP420 →	+0.488	+2.382	.002	.003	3	2
LUSC	RNA5SP407 →	+0.633	+7.924	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

ATP2B2-IT1 by ARL6IP5 expression — UCEC

Explore this box plot interactively →