ARL6IP5

Across TCGA cell cohorts, ARL6IP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,762 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARL6IP5-associated GO terms across cancer lineages are Regulation of L-glutamate import across plasma membrane, Regulation of amino acid import across plasma membrane, and Regulation of amino acid transmembrane transport. Each is linked with ARL6IP5 in more than 18 cancer types. Because this analysis shows association rather than direction, both ARL6IP5-to-partner and partner-to-ARL6IP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of L-glutamate import across plasma membrane grouped by ARL6IP5-low versus ARL6IP5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6IP5→partner) and Y-score (partner→ARL6IP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of L-glutamate import across plasma membrane →	+0.275	+1.835	<.001	<.001	3	19
BONE	Regulation of amino acid import across plasma membrane →	+0.230	+1.469	<.001	<.001	3	11
BONE	Regulation of amino acid transmembrane transport →	+0.230	+1.469	<.001	<.001	3	11
BONE	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.151	-1.373	<.001	<.001	3	11
BONE	rRNA pseudouridine synthesis →	-0.122	-1.302	<.001	<.001	3	11
BONE	Ribosome biogenesis →	-0.154	-2.154	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,762 associations by consensus.

Regulation of L-glutamate import across plasma membrane by ARL6IP5 expression — BLOOD_Myeloma

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