ARL6IP4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARL6IP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,168 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ARL6IP4-associated GO terms across cancer lineages are Regulation of telomere maintenance in response to DNA damage, NADH dehydrogenase complex assembly, and Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. Each is linked with ARL6IP4 in more than 28 cancer types. Because this analysis shows association rather than direction, both ARL6IP4-to-partner and partner-to-ARL6IP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance in response to DNA damage grouped by ARL6IP4-low versus ARL6IP4-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6IP4→partner) and Y-score (partner→ARL6IP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
DLBCRegulation of telomere maintenance in response to DNA damage →+0.046+0.747.001<.001229
STADNADH dehydrogenase complex assembly →+0.052+0.283<.001<.001327
UVMObsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →+0.049+0.377<.001<.001327
KIRCRegulation of DNA strand elongation →+0.059+0.712<.001<.001326
ESCAIron-sulfur cluster assembly →+0.054+0.274.002<.001326
STADMitochondrial translation →+0.049+0.218<.001<.001326
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,168 associations by consensus.

Regulation of telomere maintenance in response to DNA damage by ARL6IP4 expression — DLBC

Box plot of Regulation of telomere maintenance in response to DNA damage in ARL6IP4-low vs ARL6IP4-high samples in DLBC.

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Exploration