ARL6IP4

Across TCGA cell cohorts, ARL6IP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,953 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARL6IP4-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Regulation of anaphase-promoting complex-dependent catabolic process, and Methylglyoxal metabolic process. Each is linked with ARL6IP4 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARL6IP4-to-partner and partner-to-ARL6IP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by ARL6IP4-low versus ARL6IP4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6IP4→partner) and Y-score (partner→ARL6IP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.166	+0.567	.003	<.001	3	9
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.222	+0.569	.005	.001	3	9
SKIN	Methylglyoxal metabolic process →	+0.076	+0.381	.009	.005	2	9
BLOOD_Myeloma	Translation reinitiation →	+0.113	+0.891	<.001	.001	3	8
BREAST	7-methylguanosine cap hypermethylation →	+0.073	+0.499	.003	.007	3	7
URINARY_TRACT	mRNA cis splicing, via spliceosome →	+0.077	+0.570	.005	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,953 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by ARL6IP4 expression — BONE

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