ARL6

Across TCGA cell cohorts, ARL6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,575 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARL6-associated GO terms across cancer lineages are Protein localization to non-motile cilium, Protein localization to cilium, and Regulation of microtubule-based process. Each is linked with ARL6 in more than 17 cancer types. Because this analysis shows association rather than direction, both ARL6-to-partner and partner-to-ARL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to non-motile cilium grouped by ARL6-low versus ARL6-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6→partner) and Y-score (partner→ARL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein localization to non-motile cilium →	+0.129	+1.655	<.001	<.001	3	18
STOMACH	Protein localization to cilium →	+0.077	+1.644	<.001	<.001	3	17
STOMACH	Regulation of microtubule-based process →	+0.057	+1.224	<.001	<.001	3	15
BREAST	Receptor localization to non-motile cilium →	+0.628	+0.851	.006	<.001	2	14
LUNG_NSCLC_LUAD	Protein localization to ciliary membrane →	+0.104	+0.633	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.073	+0.707	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,575 associations by consensus.

Protein localization to non-motile cilium by ARL6 expression — STOMACH

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