ARL6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARL6 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARL6-associated genes across cancer lineages are CD300H. Each is linked with ARL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL6-to-partner and partner-to-ARL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by ARL6-low versus ARL6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6→partner) and Y-score (partner→ARL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECD300H →+0.033+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD300H by ARL6 expression — LARGE_INTESTINE

Box plot of CD300H in ARL6-low vs ARL6-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration