Across TCGA pan-cancer cohorts, ARL5AP3 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated ARL5AP3 data layer.
The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ARL5AP3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ARL5AP3 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.
UCS, COAD, and UCEC are the cancer types where ARL5AP3 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.