Across TCGA patient cohorts, ARL4C protein abundance is significantly associated with the RNA expression of many other genes, with 6,274 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ARL4C-associated genes across cancer lineages are MFAP2, CALD1, and FN1. Each is linked with ARL4C in more than 5 cancer types. Because this analysis shows association rather than direction, both ARL4C-to-partner and partner-to-ARL4C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4C→partner) and Y-score (partner→ARL4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MFAP2 →	+1.411	+0.717	<.001	<.001	3	6
BRCA	CALD1 →	+1.356	+0.858	<.001	<.001	3	5
BRCA	FN1 →	+1.759	+0.725	<.001	<.001	3	5
HNSC	POSTN →	+2.050	+0.617	<.001	<.001	3	5
BRCA	ADAM12 →	+1.404	+0.594	<.001	.001	3	5
BRCA	PLOD2 →	+1.131	+0.731	.004	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,274 associations by consensus.

Exploration

ARL4C survival (RNA) · tumor vs normal (RNA) · all ARL4C data types