Across TCGA patient cohorts, ARL4C mutation is significantly associated with the RNA expression of many other genes, with 2,731 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL4C-associated genes across cancer lineages are ZNF479, RNU6-31P, and NANOGP10. Each is linked with ARL4C in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL4C-to-partner and partner-to-ARL4C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4C→partner) and Y-score (partner→ARL4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZNF479 →	+0.026	+5.254	.002	.001	3	2
SKCM	RNU6-31P →	+0.391	+4.500	<.001	.005	3	2
STAD	NANOGP10 →	+0.183	+4.532	<.001	.001	3	2
UCEC	FAM243A →	+0.011	+4.422	<.001	.002	3	2
SKCM	E2F6P1 →	+0.051	+4.594	<.001	.008	3	2
UCEC	HMGB3P15 →	+0.056	+2.049	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,731 associations by consensus.

Exploration

ARL4C survival (RNA) · tumor vs normal (RNA) · all ARL4C data types