Across TCGA patient cohorts, ARL4C mutation is significantly associated with the total protein of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL4C-associated genes across cancer lineages are INPP4B, 14-3-3_beta, and EGFR_pY1068. Each is linked with ARL4C in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL4C-to-partner and partner-to-ARL4C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL4C→partner) and Y-score (partner→ARL4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.254	-2.115	.029	.016	3	2
UCEC	14-3-3_beta →	-0.093	-1.912	.009	.005	3	1
UCEC	EGFR_pY1068 →	-0.367	-2.807	<.001	<.001	3	1
UCEC	eIF4E →	+0.168	+2.472	.027	.010	3	1
UCEC	FASN →	+0.482	+2.321	<.001	.001	3	1
UCEC	FoxM1 →	+0.329	+2.807	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

Exploration

ARL4C survival (RNA) · tumor vs normal (RNA) · all ARL4C data types