ARL3

Across TCGA patient cohorts, ARL3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,468 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARL3-associated genes across cancer lineages are CUEDC2, LCA5, and FAM229B. Each is linked with ARL3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARL3-to-partner and partner-to-ARL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARL3 versus CUEDC2 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL3→partner) and Y-score (partner→ARL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CUEDC2 →	+0.646	+0.510	<.001	<.001	3	7
UCEC	LCA5 →	+0.715	+0.391	<.001	<.001	3	7
UCEC	FAM229B →	+0.979	+0.428	.002	<.001	3	7
CCRCC	MXI1 →	+0.712	+0.303	<.001	<.001	3	6
HNSC	AZIN2 →	+0.434	+0.304	<.001	<.001	3	6
BRCA	SFXN2 →	+0.916	+0.451	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,468 associations by consensus.

ARL3 vs CUEDC2 — OV

Explore this scatter interactively →