ARL2BPP8

Across TCGA pan-cancer cohorts, ARL2BPP8 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated ARL2BPP8 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher ARL2BPP8 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARL2BPP8 expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

CESC, ACC, and UCEC are the cancer types where ARL2BPP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.146	0.743	<.001	126	view →
ACC	DFS	Tertile	All	0.046	0.753	<.001	108	view →
UCEC	OS	Tertile	III,IV	0.551	0.836	<.001	96	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LUSC	OS	Tertile	All	0.352	0.681	.003	75	view →
SKCM	DFS	Tertile	All	0.234	0.614	.013	42	view →
GBM	OS	Tertile	All	0.128	0.418	.007	27	view →
BLCA	OS	Tertile	III,IV	0.185	0.579	.025	9	view →
STAD	OS	Quartile	IV	0.825	0.331	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

ARL2BPP8–CESC (DFS)

Open the CESC breakdown →