ARL2BP

Across TCGA patient cohorts, ARL2BP RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible ARL2BP-associated GO terms across cancer lineages are Negative regulation of protein sumoylation, Negative regulation of telomere capping, and Citrate metabolic process. Each is linked with ARL2BP in more than 29 cancer types. Because this analysis shows association rather than direction, both ARL2BP-to-partner and partner-to-ARL2BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein sumoylation grouped by ARL2BP-low versus ARL2BP-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL2BP→partner) and Y-score (partner→ARL2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Negative regulation of protein sumoylation →	+0.090	+1.020	<.001	<.001	3	30
THYM	Negative regulation of telomere capping →	+0.086	+1.618	<.001	<.001	3	29
THYM	Citrate metabolic process →	+0.080	+1.599	<.001	<.001	3	29
DLBC	Regulation of translational initiation by eIF2 alpha phosphorylation →	+0.081	+1.163	<.001	<.001	3	28
DLBC	Establishment of mitotic sister chromatid cohesion →	+0.097	+1.628	<.001	<.001	3	28
THYM	Vesicle cargo loading →	+0.083	+1.526	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

Negative regulation of protein sumoylation by ARL2BP expression — TGCT

Explore this box plot interactively →