ARL2BP

Across TCGA patient cohorts, ARL2BP mutation is significantly associated with the RNA expression of many other genes, with 89 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL2BP-associated genes across cancer lineages are MIR4790, RNU6-989P, and NDE1P2. Each is linked with ARL2BP in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL2BP-to-partner and partner-to-ARL2BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4790 grouped by ARL2BP-low versus ARL2BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL2BP→partner) and Y-score (partner→ARL2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4790 →	+0.404	+4.722	<.001	.004	3	2
LUSC	RNU6-989P →	+0.312	+7.924	<.001	.008	3	1
UCEC	NDE1P2 →	+0.082	+4.358	<.001	.001	3	1
UCEC	TMEM271 →	+0.374	+3.677	<.001	.006	3	1
COAD	IFNA8 →	+0.184	+6.392	<.001	.001	3	1
COAD	STATH →	+0.183	+5.516	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

MIR4790 by ARL2BP expression — UCEC

Explore this box plot interactively →