ARL2BP

Across TCGA cell cohorts, ARL2BP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,743 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARL2BP-associated GO terms across cancer lineages are Negative regulation of organelle assembly, Positive regulation of translational initiation, and Vesicle cargo loading. Each is linked with ARL2BP in more than 10 cancer types. Because this analysis shows association rather than direction, both ARL2BP-to-partner and partner-to-ARL2BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of organelle assembly grouped by ARL2BP-low versus ARL2BP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL2BP→partner) and Y-score (partner→ARL2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of organelle assembly →	+0.114	+1.064	<.001	<.001	3	11
BREAST	Positive regulation of translational initiation →	+0.099	+0.862	<.001	<.001	3	11
BONE	Vesicle cargo loading →	+0.144	+1.201	<.001	<.001	3	10
BONE	Phospholipid dephosphorylation →	+0.062	+0.960	<.001	.002	3	9
PANCREAS	Phosphatidylinositol dephosphorylation →	+0.065	+0.833	<.001	<.001	3	9
BONE	Negative regulation of cell cycle G1/S phase transition →	+0.077	+1.070	.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,743 associations by consensus.

Negative regulation of organelle assembly by ARL2BP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →