Across TCGA patient cohorts, ARL2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL2-associated genes across cancer lineages are cDC, pDC, and Osteoblast. Each is linked with ARL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL2-to-partner and partner-to-ARL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL2→partner) and Y-score (partner→ARL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cDC →	+0.138	+3.178	.001	.010	3	1
UCEC	pDC →	+0.062	+2.839	.014	.034	3	1
UCEC	Osteoblast →	-0.059	-3.300	.013	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

ARL2 survival (RNA) · tumor vs normal (RNA) · all ARL2 data types