Across TCGA patient cohorts, ARL17A mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL17A-associated genes across cancer lineages are EEF1E1-BLOC1S5, MRPL32P1, and TXNP2. Each is linked with ARL17A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL17A-to-partner and partner-to-ARL17A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL17A→partner) and Y-score (partner→ARL17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EEF1E1-BLOC1S5 →	+0.120	+6.453	<.001	.001	3	1
UCEC	MRPL32P1 →	+0.477	+5.694	<.001	.003	3	1
UCEC	TXNP2 →	+0.272	+5.694	<.001	.003	3	1
UCEC	PSMA6P3 →	+0.535	+5.242	<.001	.007	3	1
UCEC	SNRPGP7 →	+0.590	+6.335	<.001	.001	3	1
UCEC	TMEM248P1 →	+0.116	+5.186	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

ARL17A survival (RNA) · tumor vs normal (RNA) · all ARL17A data types