Across TCGA cell cohorts, ARL16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,119 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARL16-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Microtubule polymerization, and Mitotic cell cycle checkpoint signaling. Each is linked with ARL16 in more than 11 cancer types. Because this analysis shows association rather than direction, both ARL16-to-partner and partner-to-ARL16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL16→partner) and Y-score (partner→ARL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.130	+0.844	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Microtubule polymerization →	+0.103	+1.025	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic cell cycle checkpoint signaling →	+0.104	+0.882	.003	.003	3	12
BONE	Negative regulation of RIG-I signaling pathway →	+0.146	+0.707	.009	.006	3	11
LARGE_INTESTINE	Epigenetic regulation of gene expression →	+0.038	+0.522	.004	.005	3	11
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.094	+0.999	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,119 associations by consensus.

Exploration

ARL16 survival (RNA) · tumor vs normal (RNA) · all ARL16 data types