Across TCGA cell cohorts, ARL16 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARL16-associated genes across cancer lineages are TSHB, OR10K2, and OR10T2. Each is linked with ARL16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL16-to-partner and partner-to-ARL16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL16→partner) and Y-score (partner→ARL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TSHB →	+0.120	+4.276	.005	.007	3	1
BLOOD_Leukemia	OR10K2 →	+0.060	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR10T2 →	+0.889	+4.276	<.001	.007	3	1
BLOOD_Leukemia	OR10R2 →	+1.909	+4.551	<.001	.004	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ARL16 survival (RNA) · tumor vs normal (RNA) · all ARL16 data types