Across TCGA patient cohorts, ARL15 mutation is significantly associated with the RNA expression of many other genes, with 1,123 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL15-associated genes across cancer lineages are POLR2DP2, RNA5SP423, and RNU6-650P. Each is linked with ARL15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL15-to-partner and partner-to-ARL15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL15→partner) and Y-score (partner→ARL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLR2DP2 →	+0.089	+2.359	.004	.005	3	2
UCEC	RNA5SP423 →	+0.732	+1.939	<.001	.007	3	2
BLCA	RNU6-650P →	+0.496	+5.038	<.001	.009	3	2
CESC	RNA5SP367 →	+0.331	+5.010	<.001	.009	3	2
BRCA	GAGE2E →	+0.432	+7.234	<.001	<.001	3	1
BRCA	MIR6858 →	+0.506	+5.646	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,123 associations by consensus.

Exploration

ARL15 survival (RNA) · tumor vs normal (RNA) · all ARL15 data types