Across TCGA cell cohorts, ARL15 mutation is significantly associated with the RNA expression of many other genes, with 395 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARL15-associated genes across cancer lineages are ANKRD54, CBY1, and MCM5. Each is linked with ARL15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL15-to-partner and partner-to-ARL15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL15→partner) and Y-score (partner→ARL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANKRD54 →	+0.512	+3.299	.003	.004	3	1
LARGE_INTESTINE	CBY1 →	+0.646	+3.299	.001	.004	3	1
LARGE_INTESTINE	MCM5 →	+0.919	+3.234	<.001	.004	3	1
LARGE_INTESTINE	TNRC6B →	+0.958	+3.064	<.001	.009	3	1
LARGE_INTESTINE	TRMU →	+0.704	+3.212	<.001	.006	3	1
LARGE_INTESTINE	CDH20 →	+0.080	+2.667	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 395 associations by consensus.

Exploration

ARL15 survival (RNA) · tumor vs normal (RNA) · all ARL15 data types