Across TCGA cell cohorts, ARIH2OS mutation is significantly associated with the mutation status of many other genes, with 83 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARIH2OS-associated genes across cancer lineages are SPINK8, FGF21, and SLC39A7. Each is linked with ARIH2OS in more than 1 cancer types. Because this analysis shows association rather than direction, both ARIH2OS-to-partner and partner-to-ARIH2OS results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARIH2OS→partner) and Y-score (partner→ARIH2OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPINK8 →	+5.523	+5.523	.003	.003	1	2
LARGE_INTESTINE	FGF21 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	SLC39A7 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	CD27 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	TOMM40L →	+5.523	+5.523	.003	.003	1	2
LARGE_INTESTINE	NUDT5 →	+5.523	+5.523	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

Exploration

ARIH2OS survival (RNA) · tumor vs normal (RNA) · all ARIH2OS data types