ARIH2

Across TCGA cell cohorts, ARIH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,267 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARIH2-associated GO terms across cancer lineages are DNA-templated transcription elongation, Regulation of mRNA stability, and Regulation of double-strand break repair via homologous recombination. Each is linked with ARIH2 in more than 16 cancer types. Because this analysis shows association rather than direction, both ARIH2-to-partner and partner-to-ARIH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription elongation grouped by ARIH2-low versus ARIH2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARIH2→partner) and Y-score (partner→ARIH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DNA-templated transcription elongation →	+0.104	+0.869	<.001	<.001	3	17
SOFT_TISSUE	Regulation of mRNA stability →	+0.062	+0.659	<.001	.005	3	16
SOFT_TISSUE	Regulation of double-strand break repair via homologous recombination →	+0.086	+0.694	.002	.004	3	15
SOFT_TISSUE	Transcription initiation at RNA polymerase I promoter →	+0.140	+0.993	<.001	<.001	3	15
SOFT_TISSUE	Regulation of DNA repair →	+0.077	+0.867	<.001	<.001	3	15
BLOOD_Lymphoma	mRNA destabilization →	+0.070	+0.784	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,267 associations by consensus.

DNA-templated transcription elongation by ARIH2 expression — OVARY

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