ARIH1

Across TCGA cell cohorts, ARIH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,393 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARIH1-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription initiation, Negative regulation of transcription initiation by RNA polymerase II, and Endosomal transport. Each is linked with ARIH1 in more than 17 cancer types. Because this analysis shows association rather than direction, both ARIH1-to-partner and partner-to-ARIH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription initiation grouped by ARIH1-low versus ARIH1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARIH1→partner) and Y-score (partner→ARIH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.141	+0.756	.001	.001	2	18
STOMACH	Negative regulation of transcription initiation by RNA polymerase II →	+0.141	+0.756	.001	.001	2	18
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.065	+0.873	<.001	<.001	3	16
OESOPHAGUS	Regulation of translational initiation →	+0.090	+0.862	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.070	+0.934	.002	.003	3	16
BONE	Epigenetic regulation of gene expression →	+0.063	+0.787	.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,393 associations by consensus.

Negative regulation of DNA-templated transcription initiation by ARIH1 expression — STOMACH

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