ARID5B

Across TCGA patient cohorts, ARID5B mutation is significantly associated with the RNA expression of many other genes, with 3,046 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID5B-associated genes across cancer lineages are MIR190B, TTI2, and TLCD3A. Each is linked with ARID5B in more than 3 cancer types. Because this analysis shows association rather than direction, both ARID5B-to-partner and partner-to-ARID5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR190B grouped by ARID5B-low versus ARID5B-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID5B→partner) and Y-score (partner→ARID5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR190B →	+0.236	+4.423	<.001	.007	3	4
UCEC	TTI2 →	+0.382	+1.821	<.001	<.001	3	4
UCEC	TLCD3A →	+0.350	+1.198	.006	.001	3	4
UCEC	TIPIN →	+0.439	+1.573	<.001	<.001	3	4
UCEC	UHRF1 →	+0.649	+1.958	<.001	<.001	3	3
UCEC	RN7SL478P →	+0.104	+1.280	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,046 associations by consensus.

MIR190B by ARID5B expression — LIHC

Explore this box plot interactively →