ARID5B

Across TCGA patient cohorts, ARID5B mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID5B-associated genes across cancer lineages are eEF2, 4E-BP1, and JNK_pT183_Y185. Each is linked with ARID5B in more than 3 cancer types. Because this analysis shows association rather than direction, both ARID5B-to-partner and partner-to-ARID5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ARID5B-low versus ARID5B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID5B→partner) and Y-score (partner→ARID5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.222	+0.912	.016	.032	3	4
UCEC	4E-BP1 →	+0.219	+1.292	.001	.010	3	4
UCEC	JNK_pT183_Y185 →	-0.135	-1.347	.002	.005	3	3
UCEC	Annexin-1 →	+0.311	+1.019	.023	.042	3	3
UCEC	c-Kit →	-0.189	-1.624	.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.351	+1.392	.016	.015	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

eEF2 by ARID5B expression — UCEC

Explore this box plot interactively →