ARID5B

Across TCGA cell cohorts, ARID5B mutation is significantly associated with the RNA expression of many other genes, with 325 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARID5B-associated genes across cancer lineages are ARMH2, PRR27, and CST11. Each is linked with ARID5B in more than 2 cancer types. Because this analysis shows association rather than direction, both ARID5B-to-partner and partner-to-ARID5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARMH2 grouped by ARID5B-low versus ARID5B-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID5B→partner) and Y-score (partner→ARID5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ARMH2 →	+0.037	+3.643	<.001	.002	3	3
PANCREAS	PRR27 →	+0.013	+4.029	<.001	.007	3	1
BLOOD_Lymphoma	CST11 →	+0.582	+2.807	<.001	.004	3	1
BLOOD_Lymphoma	ARL5C →	+0.077	+3.600	.001	.002	3	1
BLOOD_Lymphoma	KCNH6 →	+0.050	+3.678	<.001	.001	3	1
BLOOD_Lymphoma	ZNF705G →	+0.003	+2.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 325 associations by consensus.

ARMH2 by ARID5B expression — OVARY

Explore this box plot interactively →