ARID4B

Across TCGA patient cohorts, ARID4B mutation is significantly associated with the RNA expression of many other genes, with 3,858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID4B-associated genes across cancer lineages are ZNF724, GUF1, and PTMAP4. Each is linked with ARID4B in more than 3 cancer types. Because this analysis shows association rather than direction, both ARID4B-to-partner and partner-to-ARID4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF724 grouped by ARID4B-low versus ARID4B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID4B→partner) and Y-score (partner→ARID4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZNF724 →	+0.606	+3.182	<.001	.009	3	4
SKCM	GUF1 →	+0.724	+3.706	<.001	<.001	3	4
UCEC	PTMAP4 →	+0.528	+1.758	.008	.003	3	4
UCEC	YWHAE →	+0.247	+1.732	.002	<.001	3	3
UCEC	GRPEL1 →	+0.310	+2.201	<.001	<.001	3	3
SKCM	NCAPG →	+0.802	+3.195	.007	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,858 associations by consensus.

ZNF724 by ARID4B expression — SKCM

Explore this box plot interactively →