ARID4B

Across TCGA patient cohorts, ARID4B mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID4B-associated genes across cancer lineages are ASNS, eIF4G, and FoxM1. Each is linked with ARID4B in more than 2 cancer types. Because this analysis shows association rather than direction, both ARID4B-to-partner and partner-to-ARID4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ARID4B-low versus ARID4B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID4B→partner) and Y-score (partner→ARID4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.283	+1.321	.004	.024	3	3
UCEC	eIF4G →	+0.181	+1.678	.034	.019	3	2
UCEC	FoxM1 →	+0.195	+1.540	.006	.001	3	2
UCEC	PCNA →	+0.190	+1.540	.001	.001	3	2
UCEC	Annexin_VII →	-0.084	-1.050	.028	.023	3	2
UCEC	ATM →	-0.476	-2.057	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

ASNS by ARID4B expression — UCEC

Explore this box plot interactively →