ARID4B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARID4B mutation is significantly associated with the RNA expression of many other genes, with 760 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARID4B-associated genes across cancer lineages are ELOA3P, CCDC134, and CSPG5. Each is linked with ARID4B in more than 2 cancer types. Because this analysis shows association rather than direction, both ARID4B-to-partner and partner-to-ARID4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3P grouped by ARID4B-low versus ARID4B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID4B→partner) and Y-score (partner→ARID4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaELOA3P →+0.151+3.977<.001<.00133
LARGE_INTESTINECCDC134 →+0.750+2.502.001.00532
LARGE_INTESTINECSPG5 →+0.875+2.588<.001.00432
LARGE_INTESTINEZC2HC1C →+0.559+2.502.002.00532
LARGE_INTESTINESPATA1 →+0.504+2.502<.001.00532
LARGE_INTESTINEMMS22L →+0.675+2.588.007.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 760 associations by consensus.

ELOA3P by ARID4B expression — BLOOD_Leukemia

Box plot of ELOA3P in ARID4B-low vs ARID4B-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration