Across TCGA patient cohorts, ARID3C mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID3C-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and JNK2. Each is linked with ARID3C in more than 1 cancer types. Because this analysis shows association rather than direction, both ARID3C-to-partner and partner-to-ARID3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID3C→partner) and Y-score (partner→ARID3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.322	-2.321	.010	.034	3	1
UCEC	A-Raf_pS299 →	-0.177	-2.321	.003	.035	3	1
UCEC	JNK2 →	+0.307	+3.459	.002	.005	3	1
UCEC	Ku80 →	+0.328	+2.335	.005	.020	3	1
UCEC	PCNA →	+0.266	+2.321	.014	.035	3	1
UCEC	AMPK_pT172 →	+0.432	+3.000	.036	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

ARID3C survival (RNA) · tumor vs normal (RNA) · all ARID3C data types