ARID3A

Across TCGA cell cohorts, ARID3A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,883 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARID3A-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with ARID3A in more than 12 cancer types. Because this analysis shows association rather than direction, both ARID3A-to-partner and partner-to-ARID3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by ARID3A-low versus ARID3A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID3A→partner) and Y-score (partner→ARID3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription pausing by RNA polymerase II →	+0.173	+0.807	<.001	<.001	3	13
PANCREAS	Symbiont-mediated disruption of host cellular anatomical structure →	+0.087	+0.747	<.001	.001	3	12
PANCREAS	Symbiont-mediated disruption of host anatomical structure →	+0.087	+0.747	<.001	.001	3	12
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.129	+1.192	<.001	.006	3	11
STOMACH	Regulation of DNA-templated transcription initiation →	+0.068	+2.232	<.001	.003	2	12
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.129	+1.192	<.001	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,883 associations by consensus.

Transcription pausing by RNA polymerase II by ARID3A expression — BONE

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