ARID1A

Across TCGA cell cohorts, ARID1A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,212 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARID1A-associated GO terms across cancer lineages are Regulation of DNA repair, Positive regulation of double-strand break repair, and Regulation of nucleotide-excision repair. Each is linked with ARID1A in more than 18 cancer types. Because this analysis shows association rather than direction, both ARID1A-to-partner and partner-to-ARID1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by ARID1A-low versus ARID1A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID1A→partner) and Y-score (partner→ARID1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of DNA repair →	+0.095	+1.435	<.001	<.001	3	19
STOMACH	Positive regulation of double-strand break repair →	+0.105	+1.747	.005	.005	3	18
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.107	+0.812	<.001	<.001	3	18
STOMACH	RISC complex assembly →	+0.146	+1.906	.001	.001	3	17
BONE	Regulation of double-strand break repair →	+0.080	+1.041	<.001	.001	3	17
BONE	Positive regulation of DNA repair →	+0.075	+1.146	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,212 associations by consensus.

Regulation of DNA repair by ARID1A expression — BONE

Explore this box plot interactively →